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左のSSは、恒例イベント 2004年度年末特攻での記念撮影です。
LDはいわゆるまったりギルドですが、関連ギルドとして、対人ギルド LoveOppai?[LO?] や、緑頭ギルドPiccoro Yakisobany![PY!] があったりします。
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They looked at the number of antibiotic prescriptions given to more than 200,000 diabetics in the UK at least one year before they were diagnosed with the disease, and compared this to the number given to 800,000 non-diabetic patients of the same age and sex.
They found that patients prescribed at least two courses of penicillins, cephalosporines, quinolones and macrolides were at higher risk of being diagnosed with type 2 diabetes.
The risk increased with the number of antibiotic courses prescribed, says a report in the European Journal of Endocrinology (must credit).
More than 3million Britons have diabetes and nine out of ten have type 2 which occurs when the body loses the ability to process blood sugar
Patients prescribed 2-5 courses of penicillins 鈥?used for a variety of infections - increased their risk of diabetes by 8 per cent.
The risk increased by 23 per cent for those having more than five courses of penicillins.
Patients having 2-5 courses of quinolones, used in respiratory and urinary tract infections, had an increased diabetes risk of 15 per cent, which rose 37 per cent for those having more than five courses.
The risk was calculated after adjusting for other risk factors such as obesity, smoking history, heart disease and history of infections.
Study leader Dr Ben Boursi said 鈥楪ut bacteria have been suggested to influence the mechanisms behind obesity, insulin resistance and diabetes in both animal and human models.
鈥楶revious studies have shown that antibiotics can alter the digestive ecosystem.鈥?senior author Dr Yu-Xiao Yang added: 鈥榃hile our study does not show cause and effect, we think changing levels and diversity of gut bacteria could explain the link between antibiotics and diabetes risk.鈥?There was no increase in risk associated with use of antivirals or anti-fungal medications and the study found little evidence of a link between antibiotic use and the risk of type 1 diabetes.
Dr Boursi said 鈥極ver-prescription of antibiotics is already a problem around the world as bacteria become increasingly resistant to their effects.
鈥極ur findings are important, not only for understanding how diabetes may develop, but as a warning to reduce unnecessary antibiotic treatments that might do more harm than good.鈥?Prof Jodi Lindsay, Professor of Microbial Pathogenesis, St George鈥檚, University of London, said 鈥楶atients with type 2 diabetes have an increased risk of developing infections, and therefore they are more likely to be prescribed antibiotics to treat those infections.
鈥業n the year prior to diabetes diagnosis, patients may show some signs of disease and may also have a higher risk of infection, and therefore receive more antibiotics.
鈥楾his is a very large and helpful study linking diabetes with antibiotic consumption in the UK public, but at this stage we don鈥檛 know which is the chicken and which is the egg.
鈥楾he idea that antibiotics might contribute to diabetes development might be important and more research needs to be done.鈥?